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Comment
. 2018 Jul;10(7):E596-E597.
doi: 10.21037/jtd.2018.07.18.

Hydrocortisone plus fludrocortisone: Taichi of risk hedge for improving adults with septic shock

Wensen Chen  1 , Yingqin Wang  2 , Ming Zhong  2
Affiliations
Comment

Hydrocortisone plus fludrocortisone: Taichi of risk hedge for improving adults with septic shock

Wensen Chen et al. J Thorac Dis. 2018 Jul.
No abstract available

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Conflict of interest statement

Conflicts of Interest: The authors have no conflicts of interest to declare.

Comment on

  • Hydrocortisone plus Fludrocortisone for Adults with Septic Shock.
    Annane D, Renault A, Brun-Buisson C, Megarbane B, Quenot JP, Siami S, Cariou A, Forceville X, Schwebel C, Martin C, Timsit JF, Misset B, Ali Benali M, Colin G, Souweine B, Asehnoune K, Mercier E, Chimot L, Charpentier C, François B, Boulain T, Petitpas F, Constantin JM, Dhonneur G, Baudin F, Combes A, Bohé J, Loriferne JF, Amathieu R, Cook F, Slama M, Leroy O, Capellier G, Dargent A, Hissem T, Maxime V, Bellissant E; CRICS-TRIGGERSEP Network. Annane D, et al. N Engl J Med. 2018 Mar 1;378(9):809-818. doi: 10.1056/NEJMoa1705716. N Engl J Med. 2018. PMID: 29490185 Clinical Trial.

References

    1. Annane D, Renault A, Brun-Buisson C, et al. Hydrocortisone plus Fludrocortisone for Adults with Septic Shock. N Engl J Med 2018;378:809-18. 10.1056/NEJMoa1705716 - DOI - PubMed
    1. Venkatesh B, Finfer S, Cohen J, et al. Adjunctive Glucocorticoid Therapy in Patients with Septic Shock. N Engl J Med 2018;378:797-808. 10.1056/NEJMoa1705835 - DOI - PubMed
    1. Druce LA, Thorpe CM, Wilton A. Mineralocorticoid effects due to cortisol inactivation overload explain the beneficial use of hydrocortisone in septic shock. Med Hypotheses 2008;70:56-60. 10.1016/j.mehy.2007.04.031 - DOI - PubMed
    1. Rhodes A, Evans LE, Alhazzani W, et al. Surviving Sepsis Campaign: International Guidelines for Management of Sepsis and Septic Shock: 2016. Crit Care Med 2017;45:486-552. 10.1097/CCM.0000000000002255 - DOI - PubMed

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