Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2016 Sep:1:10.
doi: 10.21037/ales.2016.09.04. Epub 2016 Sep 29.

Fluorescence-guided laparoscopic hepatectomy

Thinzar M Lwin  1   2 , Jason K Sicklick  1 , Robert M Hoffinan  1   2 , Michael Bouvet  1   2
Affiliations

Fluorescence-guided laparoscopic hepatectomy

Thinzar M Lwin et al. Ann Laparosc Endosc Surg. 2016 Sep.
No abstract available

PubMed Disclaimer

Conflict of interest statement

Conflicts of Interest: The authors have no conflicts of interest to declare.

Figures

Figure 1
Figure 1
Tumors labeled with a telomerase-dependent adenovirus (OBP-401) expressing green fluorescent protein undergo bright-light surgery and fluorescence-guided surgery 3 days post infection. Residual cancer cells were detectable in the resection bed for the BLS group, but not the FGS group (18). BLS, bright light surgery; FGS, fluorescence-guided surgery.
Figure 2
Figure 2
Comparison of fluorescence intensity of locally-recurrent tumors after bright light surgery (BLS) or FGS with adenovirus vector expressing GFP (OBP-401) in a colon cancer liver metastasis model (18). Kaplan Meyer shows improved overall survival after FGS with adenovirus vector compared to BLS. FGS, fluorescence-guided surgery.
See this image and copyright information in PMC

References

    1. Pawlik TM, Scoggins CR, Zorzi D, et al. Effect of surgical margin status on survival and site of recurrence after hepatic resection for colorectal metastases. Ann Surg 2005;241:715–22, discussion 722-4. - PMC - PubMed
    1. Peloso A, Franchi E, Canepa MC, et al. Combined use of intraoperative ultrasound and indocyanine green fluorescence imaging to detect liver metastases from colorectal cancer. HPB (Oxford) 2013;15:928–34. - PMC - PubMed
    1. Miller DE, Gleason WL, Mcintosh HD. A comparison of the cardiac output determination by the direct Fick method and the dye-dilution method using indocyanine green dye and a cuvette densitometer. J Lab Clin Med 1962;59:345–50. - PubMed
    1. Jonak C, Skvara H, Kunstfeld R, et al. Intradeimal indocyanine green for in vivo fluorescence laser scanning microscopy of human skin: a pilot study. PLoS One 2011;6:e23972. - PMC - PubMed
    1. Schaafsma BE, Mieog JS, Hutteman M, et al. The clinical use of indocyanine green as a near-infrared fluorescent contrast agent for image-guided oncologic surgery. J Surg Oncol 2011;104:323–32. - PMC - PubMed

LinkOut - more resources