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Randomized Controlled Trial
. 2018 Sep 3;13(1):151.
doi: 10.1186/s13023-018-0884-5.

Manual and educational therapy in the treatment of hemophilic arthropathy of the elbow: a randomized pilot study

Rubén Cuesta-Barriuso  1   2   3 , Antonia Gómez-Conesa  4 , José-Antonio López-Pina  5
Affiliations
Randomized Controlled Trial

Manual and educational therapy in the treatment of hemophilic arthropathy of the elbow: a randomized pilot study

Rubén Cuesta-Barriuso et al. Orphanet J Rare Dis. .

Abstract

Background: Elbow arthropathy is characteristic in patients with hemophilia. Arthropathy is manifested by decreased range of motion, pain, loss of strength and muscular atrophy, and axial changes. The objective is to evaluate the safety of two physiotherapy programs combining manual therapy and home exercises with educational sessions in patients with hemophilic elbow arthropathy.

Methods: This is a randomized study with 27 patients with elbow hemophilic arthropathy with a mean age of 34.48 (SD: 12.99) years, were randomised to Manual Therapy group, educational group and control group. The physiotherapy programmes were: manual therapy through joint traction, passive muscles stretching and proprioceptive neuromuscular facilitation; and educational sessions and daily home exercises. The study lasted for twelve weeks, with two sessions a week in manual therapy group and one session every two weeks with daily home exercises in educational group. The variables measured were range of motion of elbow, biceps strength, circumference of arm, and elbow pain.

Results: The treatment with manual therapy improved the circumference of arm, flexion elbow and elbow pain. Six months later, MT group still enjoyed improved. In the educational group there were improvements, but not significant, in the measured variables.

Conclusion: Neither of the two physiotherapy interventions caused elbow hemarthrosis. The treatment with manual therapy improved the range of movement and circumference of arm, and lessened pain in hemophilic patients with chronic elbow arthropathy. No hemarthrosis was recorded during treatment or during the follow-up period. Larger randomized clinical trials are required to confirm the results of this study.

Trial registration: ( NCT02198040 ). Registered 22 July 2014, retrospectively registered.

Keywords: Elbow; Hemophilia; Joint disease; Physiotherapy modalities.

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Conflict of interest statement

Ethics approval and consent to participate

The protocol was approved by the Ethics Committee of the University of Murcia (registration number 43/2011). The study was registered in the International Registry (NCT02198040).

Consent for publication

Consent for publication was obtained from all participants.

Competing interests

The authors declare that they have no competing interests.

Publisher’s Note

Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

Figures

Fig. 1
Fig. 1
CONSORT Flow Diagram of the study (Additional file 1)
See this image and copyright information in PMC

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