Activation of a D-form of rabbit muscle glycogen synthase by Ca2+-activated protease
- PMID: 3017753
- DOI: 10.1016/0014-5793(86)80853-5
Activation of a D-form of rabbit muscle glycogen synthase by Ca2+-activated protease
Abstract
Glycogen synthase isolated from rabbit skeletal muscle as a D-form (synthase D2) is activated by a rat liver cytosolic protein differing from any of the known protein phosphatases (D2 activase). Although reversible by phosphorylation by cyclic AMP-dependent protein kinase, the activation is a result of limited proteolysis by D2 activase, which has been identified as the Ca2+-activated protease.
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