Modulating NAD⁺ metabolism to prevent acute kidney injury

Heerajnarain Bulluck¹, Derek J Hausenloy^{2

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Affiliations

¹ Norfolk and Norwich University Hospital, Norfolk, UK.
² The Hatter Cardiovascular Institute, University College London, London, UK. derek.hausenloy@duke-nus.edu.sg.
³ National Institute of Health Research University College London Hospitals Biomedical Research Centre, London, UK. derek.hausenloy@duke-nus.edu.sg.
⁴ National Heart Centre, Singapore, Singapore. derek.hausenloy@duke-nus.edu.sg.
⁵ Barts Heart Centre, St Bartholomew's Hospital, London, UK. derek.hausenloy@duke-nus.edu.sg.
⁶ Cardiovascular and Metabolic Disorders Program, Duke-National University of Singapore Medical School, Singapore, Singapore. derek.hausenloy@duke-nus.edu.sg.
⁷ Yong Loo Lin School of Medicine, National University Singapore, Singapore, Singapore. derek.hausenloy@duke-nus.edu.sg.

Comment

Heerajnarain Bulluck et al. Nat Med. 2018 Sep.

. 2018 Sep;24(9):1306-1307.

doi: 10.1038/s41591-018-0181-9.

Heerajnarain Bulluck¹, Derek J Hausenloy^{2

3

4

5

6

7}

¹ Norfolk and Norwich University Hospital, Norfolk, UK.
² The Hatter Cardiovascular Institute, University College London, London, UK. derek.hausenloy@duke-nus.edu.sg.
³ National Institute of Health Research University College London Hospitals Biomedical Research Centre, London, UK. derek.hausenloy@duke-nus.edu.sg.
⁴ National Heart Centre, Singapore, Singapore. derek.hausenloy@duke-nus.edu.sg.
⁵ Barts Heart Centre, St Bartholomew's Hospital, London, UK. derek.hausenloy@duke-nus.edu.sg.
⁶ Cardiovascular and Metabolic Disorders Program, Duke-National University of Singapore Medical School, Singapore, Singapore. derek.hausenloy@duke-nus.edu.sg.
⁷ Yong Loo Lin School of Medicine, National University Singapore, Singapore, Singapore. derek.hausenloy@duke-nus.edu.sg.

No abstract available

Comment on

De novo NAD⁺ biosynthetic impairment in acute kidney injury in humans.
Poyan Mehr A, Tran MT, Ralto KM, Leaf DE, Washco V, Messmer J, Lerner A, Kher A, Kim SH, Khoury CC, Herzig SJ, Trovato ME, Simon-Tillaux N, Lynch MR, Thadhani RI, Clish CB, Khabbaz KR, Rhee EP, Waikar SS, Berg AH, Parikh SM. Poyan Mehr A, et al. Nat Med. 2018 Sep;24(9):1351-1359. doi: 10.1038/s41591-018-0138-z. Epub 2018 Aug 20. Nat Med. 2018. PMID: 30127395 Free PMC article. Clinical Trial.