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. 2018 Nov;46(11):4399-4406.
doi: 10.1177/0300060518794249. Epub 2018 Sep 4.

Takotsubo syndrome and dialysis: an uncommon association?

Roberto Manfredini  1   2   3 , Fabio Fabbian  1   2   3 , Alfredo De Giorgi  2 , Rosaria Cappadona  1 , Beatrice Zucchi  1 , Alda Storari  2 , Maria Aurora Rodriguez Borrego  3 , Juan Manuel Carmona Torres  3 , Pablo Jesus Lopez Soto  3
Affiliations

Takotsubo syndrome and dialysis: an uncommon association?

Roberto Manfredini et al. J Int Med Res. 2018 Nov.

Abstract

This review was performed to investigate the association between treatment with dialysis and Takotsubo syndrome in patients with end-stage renal disease. We systematically explored the PubMed database using the search terms "Takotsubo cardiomyopathy" and/or "stress-induced cardiomyopathy" and/or "Takotsubo syndrome" in combination with "dialysis" and "uremia." Of 3630 articles found, 8 articles reporting 10 cases were selected for analysis. Most patients were women, and their age ranged from 51 to 84 years. Diabetes mellitus and hypertension were diagnosed in 40% of patients, and glomerular disease was diagnosed in 30%. One only patient was treated with peritoneal dialysis; all others were treated with hemodialysis. The outcome was unfavorable in only one patient. An association between Takotsubo syndrome and dialysis is uncommon, but not negligible, and comorbidities play a major role in determining the clinical outcome.

Keywords: Takotsubo syndrome; cardiomyopathy; dialysis; end-stage renal disease; outcome; review; sex.

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Figure 1.
Figure 1.
Search strategy.
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