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Review
. 2018 Dec;7(4):407-419.
doi: 10.1007/s40121-018-0210-5. Epub 2018 Sep 4.

HIV, HCV and HBV: A Review of Parallels and Differences

Maria C Leoni  1   2 , Andrew Ustianowski  3   4 , Hamzah Farooq  3 , Joop E Arends  5
Affiliations
Review

HIV, HCV and HBV: A Review of Parallels and Differences

Maria C Leoni et al. Infect Dis Ther. 2018 Dec.

Abstract

Elimination of the three blood-borne viruses-human immunodeficiency virus (HIV), hepatitis B (HBV) and hepatitis C (HCV)-as public health issues may be plausible in the near future. Spectacular advances have been made with the introduction of highly effective antiviral agents into clinical practice, and prevention strategies are available for all three infections. Effective disease control, laid out by WHO global strategies, is currently feasible for all three viruses. However, for worldwide elimination of these viruses, effective vaccines are required that are currently only available for HBV. In this review differences and parallels among HIV, HCV and HBV will be discussed with a focus on virologic and therapeutic issues, and prospects for the future of HBV will be presented.

Keywords: Antiviral therapy; Elimination; HIV virus; Hepatitis B virus; Hepatitis C virus; Vaccination.

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