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Case Reports
. 2018 Jul 25;108(8):609-610.
doi: 10.7196/SAMJ.2018.v108i8.13376.

Unmet needs of high-risk mothers reduce success of antiretroviral treatment in HIV-infected infants

Z Mvo  1 , V Ntlantsana, N Bengu, J Millar, J Roider, R Bhoola, M Krishna, Y Graza, J Van Lobenstein, C Kapongo, C Kogielambal, K Sprenger, M Archary, T Ndung'u, P Goulder
Affiliations
Case Reports

Unmet needs of high-risk mothers reduce success of antiretroviral treatment in HIV-infected infants

Z Mvo et al. S Afr Med J. .

Abstract

In the era of effective prevention of mother-to-child transmission of HIV, the same psychosocioeconomic factors that predispose to mother-to-child transmission also substantially increase the likelihood of antiretroviral therapy failure in infected infants. For HIV-infected infants to benefit from early infant diagnosis and treatment initiation, into which much funding and effort is now invested, it is vital that these unmet needs of high-risk mothers are urgently attended to. From an ongoing study of early infant diagnosis and treatment following in utero transmission in KwaZulu-Natal, South Africa, we describe four cases to highlight these challenges facing transmitting mothers that contribute to treatment failure in their infants.

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