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. 1986 Jul;204(1):115-9.
doi: 10.1007/BF00330197.

Regions associated with the stable maintenance of plasmid pSC101 and its tetracycline resistance

S Makino, C Sasakawa, H Danbara, M Yoshikawa

Regions associated with the stable maintenance of plasmid pSC101 and its tetracycline resistance

S Makino et al. Mol Gen Genet. 1986 Jul.

Abstract

Two regions tentatively called unsA and unsR were identified on pSC101. One, unsA, corresponds to less than 650 bp of the N-terminal in the tetracycline resistance structural gene and seems to inhibit stable maintenance of pSC101. The other, unsR, is defined within the 1 kb XhoI-EcoRI region located upstream of the tetracycline resistance structural gene and is a regulatory gene clearly distinct from tetR (Unger et al. 1984); it serves as a suppressor of the unsA function.

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