Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2018 Dec;27(12):2754-2760.
doi: 10.1002/pon.4881. Epub 2018 Sep 27.

Roles of positive psychological outcomes in future health perception and mental health problems: A report from the Childhood Cancer Survivor Study

Affiliations

Roles of positive psychological outcomes in future health perception and mental health problems: A report from the Childhood Cancer Survivor Study

Aurélie G Weinstein et al. Psychooncology. 2018 Dec.

Abstract

Objective: Positive psychological outcomes among adolescent and young adult survivors of childhood cancer may influence long-term health status. We examined posttraumatic growth (PTG) and Life satisfaction (LS) in adolescence, and their impact on future emotional and physical health status in young adulthood.

Methods: Survivors (n = 2802) from the Childhood Cancer Survivor Study were longitudinally analyzed across social, emotional, and physical factors during adolescence (12-17 years old), and PTG (PTG-Inventory) and LS (Cantril-Ladder-of-Life) during young adulthood (19-24 years old). The impact of PTG and LS on survivors' future long-term mental health, physical health, and social skills was also examined (23-28 years old) using Structural Equation Modeling.

Results: Survivors reported high levels of LS (M = 7.43, range 1 to 10) and a positive impact from their cancer experience (M = 48.78, range 0 to 105). Adolescent predictors of higher PTG included older age at diagnosis (p = 0.001), experiencing more severe chronic health conditions (p = 0.01), cancer recurrence/relapse (p = 0.01), and being diagnosed with a non-CNS cancer (p = 0.001). Higher perceived general health (p = 0.01), higher social skills (p = 0.001), and diagnosis with a non-CNS cancer (p = 0.02) were associated with higher LS. Higher PTG during young adulthood predicted poorer perceived health (p = 0.04) and worse emotional health (p = 0.001) in later adulthood. Higher LS predicted better emotional health (p = 0.001) and better perceived health (p = 0.001).

Conclusions: While LS was found to help survivors have better perceived long-term emotional and physical health outcomes, survivors with higher PTG fond both positive and negative impacts from cancer. Future therapeutic trials to improve LS should be considered.

Keywords: childhood cancer survivors; health perception; life satisfaction; longitudinal studies; mental health problems; positive psychological outcomes; posttraumatic growth.

PubMed Disclaimer

Figures

Figure 1:
Figure 1:
Structural regression model (second model) with all the significant standardized estimating structural paths included (p<.05). The first model includes only the variables from Baseline survey and Follow-up 2 survey. For clarity, different colors were used to draw the lines. The blue lines represent relationships with PTG, the red lines relationships with LS, and the black lines relationships with other variables. The dashed lines indicate additional significant predictors when the model is analyzed without the Follow-up 4 survey. Note: LL means Leukemia Lymphoma

Similar articles

Cited by

References

    1. Smith MY, Redd WH, Peyser C, & Vogl D (1999). Post-Traumatic Stress Disorder in Cancer: a Review. Psycho-Oncology, 8(6), 521–537. - PubMed
    1. Brinkman TM, Zhu L, Zeltzer LK, Recklitis C, Kimberg C, Zhang N, …& Krull KR (2013). Longitudinal patterns of psychological distress in adult survivors of childhood cancer. British Journal of Cancer, 109(5), 1373–1381. - PMC - PubMed
    1. Stanton AL, Bower JE, & Low CA (2006). Posttraumatic growth after cancer. Handbook of posttraumatic growth: Research and practice, 138–175.
    1. Zebrack BJ, Stuber ML, Meeske KA, Phipps S, Krull KR, Liu Q, … & Zeltzer LK (2012). Perceived positive impact of cancer among long-term survivors of childhood cancer: a report from the childhood cancer survivor study. Psycho-Oncology, 21(6), 630–639. - PMC - PubMed
    1. Armstrong GT, Kawashima T, Leisenring W, Stratton K, Stovall M, Hudson MM, … & Oeffinger KC (2014). Aging and risk of severe, disabling, life-threatening, and fatal events in the childhood cancer survivor study. Journal of Clinical Oncology, 32(12), 1218–1227. - PMC - PubMed

Publication types