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Editorial
. 2018 Aug 17;9(64):32278-32279.
doi: 10.18632/oncotarget.25964.

A metabolic vulnerability of small-cell lung cancer

Miyuki Nomura  1 , Mami Morita  1 , Nobuhiro Tanuma  1
Affiliations
Editorial

A metabolic vulnerability of small-cell lung cancer

Miyuki Nomura et al. Oncotarget. .
No abstract available

Keywords: PKM; PKM1; PKM2; SCLC; metabolism.

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Figures

Figure 1
Figure 1. PKM at the crossroads of glucose, glutamine and lactate metabolism
PPP, pentose-phosphate pathway; PEP, phosphoenol-pyruvate; TCA, tricarboxylic acid cycle; αKG, α-ketoglutarate; Mal, malate.
See this image and copyright information in PMC

References

    1. George J, et al. Nature. 2015;524:47–53. doi: 10.1038/nature14664. - DOI - PMC - PubMed
    1. Martinez-Reyes I, et al. Cell Metab. 2017;26:803–804. doi: 10.1016/j.cmet.2017.11.005. - DOI - PubMed
    1. Christofk HR, et al. Nature. 2008;452:230–233. doi: 10.1038/nature06734. - DOI - PubMed
    1. Dayton TL, et al. Genes Dev. 2016;30:1020–1033. doi: 10.1101/gad.278549.116. - DOI - PMC - PubMed
    1. Morita M, et al. Cancer Cell. 2018;33:355–367. doi: 10.1016/j.ccell.2018.02.004. - DOI - PubMed

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