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Review
. 2015 May;2(2):171-178.
doi: 10.2217/mmt.15.3. Epub 2015 May 18.

Lentigo maligna and lentigo maligna melanoma: contemporary issues in diagnosis and management

Affiliations
Review

Lentigo maligna and lentigo maligna melanoma: contemporary issues in diagnosis and management

Karen L Connolly et al. Melanoma Manag. 2015 May.

Abstract

Lentigo maligna and lentigo maligna melanomas present diagnostic and treatment dilemmas due to their frequent presence within a background of sun-damaged skin, and their location on cosmetically and functionally sensitive areas. As the incidence of this entity is increasing, diagnostic and management controversies have developed. While surgery remains the gold standard of treatment, nonsurgical treatment options are also emerging for both adjunctive and primary therapy.

Keywords: facial melanoma; lentigo maligna; lentigo maligna melanoma; melanoma; melanoma in situ.

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Conflict of interest statement

Financial & competing interests disclosure The authors have no relevant affiliations or financial involvement with any organization or entity with a financial interest in or financial conflict with the subject matter or materials discussed in the manuscript. This includes employment, consultancies, honoraria, stock ownership or options, expert testimony, grants or patents received or pending, or royalties. No writing assistance was utilized in the production of this manuscript.

Figures

<b>Figure 1.</b>
Figure 1.. Lentigo maligna, demonstrating a predominance of solitary units of melanocytes at the dermoepidermal junction and focally above it, with extension into adnexal structures.
<b>Figure 2.</b>
Figure 2.. Lentigo maligna melanoma with corresponding Wood's lamp image.
Irregular borders and various shades of brown pigmentation are seen in this patch.
<b>Figure 3.</b>
Figure 3.. Staged excision specimen demonstrates central lesion debulking and margin of peripheral tissue excised with suture orientation.
<b>Figure 4.</b>
Figure 4.. Lentigo maligna staged excision technique.
(A) Lentigo maligna after one stage of staged excision with radial sectioning. (B) Lesion after three stages of staged excision. With mapping techniques, only areas with persistent lentigo maligna undergo further excision.

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References

    1. Swetter SM, Boldrick JC, Jung SY, Egbert BM, Harvell JD. Increasing incidence of lentigo maligna melanoma subtypes: northern California and national trends 1990–2000. J. Invest. Dermatol. 2005;125(4):685–691. - PubMed
    1. Vilanova CM, Lages RB, Ribeiro SM, Almeida IP, Santos LG, Vieira SC. Epidemiological and histopathological profile of cutaneous melanoma at a center in northeastern Brazil from 2000 to 2010. An. Bras. Dermatol. 2013;88(4):545–553. - PMC - PubMed
    1. Toender A, Kjaer SK, Jensen A. Increased incidence of melanoma in situ in Denmark from 1997 to 2011: results from a nationwide population-based study. Melanoma Res. 2014;24(5):488–495. - PubMed
    1. Youl PH, Youlden DR, Baade PD. Changes in the site distribution of common melanoma subtypes in Queensland, Australia over time: implications for public health campaigns. Br. J. Dermatol. 2013;168(1):136–144. - PubMed
    1. Wu XC, Eide MJ, King J, et al. Racial and ethnic variations in incidence and survival of cutaneous melanoma in the United States, 1999–2006. J. Am. Acad. Dermatol. 2011;65(5 Suppl. 1):S26–S37. - PubMed

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