Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Editorial
. 2014 Oct;1(4):349-353.
doi: 10.2217/hep.14.18. Epub 2014 Dec 11.

The biological and clinical challenge of liver cancer heterogeneity

Affiliations
Editorial

The biological and clinical challenge of liver cancer heterogeneity

Xin Wei Wang et al. Hepat Oncol. 2014 Oct.
No abstract available

Keywords: cholangiocarcinoma; hepatocellular carcinoma; molecular subtype; precision cancer medicine; tumor genomics heterogeneity.

PubMed Disclaimer

Conflict of interest statement

Financial & competing interests disclosure The authors have no relevant affiliations or financial involvement with any organization or entity with a financial interest in or financial conflict with the subject matter or materials discussed in the manuscript. This includes employment, consultancies, honoraria, stock ownership or options, expert testimony, grants or patents received or pending, or royalties. No writing assistance was utilized in the production of this manuscript.

Figures

<b>Figure 1.</b>
Figure 1.. The etiology and features of liver cancer heterogeneity.
<b>Figure 2.</b>
Figure 2.. An integrated systems biology strategy to address tumor heterogeneity and improve outcome for liver cancer patients.
SNP: Single nucleotide polymorphism.

References

    1. Siegel R, Naishadham D, Jemal A. Cancer statistics, 2013. CA Cancer J. Clin. 2013;63:11–30. - PubMed
    1. Roessler S, Budhu A, Wang XW. Deciphering cancer heterogeneity: the biological space. Front. Cell Dev. Biol. 2014;2(12):1–5. - PMC - PubMed
    1. El-Serag HB, Rudolph KL. Hepatocellular carcinoma: epidemiology and molecular carcinogenesis. Gastroenterology. 2007;132:2557–2576. - PubMed
    1. Thorgeirsson SS, Grisham JW. Molecular pathogenesis of human hepatocellular carcinoma. Nat. Genet. 2002;31:339–346. - PubMed
    1. Budhu A, Wang XW. The role of cytokines in hepatocellular carcinoma. J. Leukoc. Biol. 2006;80:1197–1213. - PubMed

Publication types

LinkOut - more resources