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. 2018 Sep-Dec;8(3):158-164.
doi: 10.1016/j.jobcr.2016.11.004. Epub 2018 Aug 23.

Salivary glucose levels and oral candidal carriage in Type 2 diabetics

Amritaksha Bhattacharyya  1 , Shaleen Chandra  2 , Anil Singh  3 , Vineet Raj  4 , Bhavana Gupta  2
Affiliations

Salivary glucose levels and oral candidal carriage in Type 2 diabetics

Amritaksha Bhattacharyya et al. J Oral Biol Craniofac Res. 2018 Sep-Dec.

Abstract

Background: To assess the correlation between salivary glucose and blood glucose levels in diabetics and non diabetics and to study the association between salivary glucose levels and oral candidal carriage in patients with Type 2 diabetes mellitus.

Material and method: The study sample was divided into two groups, control and study group. The study group was again divided into two separate groups controlled diabetics and uncontrolled diabetics. Blood and saliva samples (for fasting and postprandial) were taken from each individual.

Results: The salivary glucose levels, highly correlated with blood glucose levels in both diabetic as well as non diabetics subjects. Salivary candidal carriage was more in oral cavity of Type 2 diabetic subjects than control subjects.

Conclusion: Saliva has the potential to be used as a noninvasive tool to monitor glycemic status of diabetic patients.

Keywords: Controlled diabetics (CD); Fasting blood glucose level (FBG); Non diabetics (ND); SGL (Salivary glucose level); Uncontrolled diabetics (UD).

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Figures

Fig. 1
Fig. 1
Salivary rinse collected in a sterile sample collection container (approx. 10 ml).
Fig. 2
Fig. 2
Salivary sample after centrifuge.
Fig. 3
Fig. 3
Streaking of sample using a sterile inoculation loop.
Fig. 4
Fig. 4
Candidal colonies on culture plates.
Fig. 5
Fig. 5
Counting of Colonies Forming Units using point tool of Image J 1.48v software.
Fig. 6
Fig. 6
Photomicrograph showing PAS positive candidal spores, some showing budding (PAS stain X 400).
Graph 1
Graph 1
Comparison of blood glucose (Bg) levels (fasting and post parandial) in study groups (Nd, Cd, and Ud).
Graph 2
Graph 2
Comparison of salivary glucose (Sg) levels (fasting and post parandial) among study groups (Nd, Cd, and Ud).
Graph 3
Graph 3
Correlation between fasting salivary glucose levels and fasting blood glucose levels.
Graph 4
Graph 4
Correlation between post prandial salivary glucose levels and post prandial blood glucose levels.
Graph 5
Graph 5
Showing CFU in nondiabetics, controlled diabetics and uncontrolled diabetic patients.
See this image and copyright information in PMC

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