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. 1986 Jul-Aug;6(4):849-51.

Receptors for epidermal growth factor in human mammary carcinomas and their metastases

A Macias, E Azavedo, R Perez, L E Rutqvist, L Skoog
  • PMID: 3019225

Receptors for epidermal growth factor in human mammary carcinomas and their metastases

A Macias et al. Anticancer Res. 1986 Jul-Aug.

Abstract

The tumor cell content of the receptor for epidermal growth factor (EGF-R) and estrogen receptor (ER) was analyzed in 36 primary breast carcinomas and their metastatic deposits. Twenty-five percent of the primary tumors and 48 percent of the metastases exhibited measurable levels of the receptor. The frequency of EGF-R positivity was the same for cutaneous and lymph node recurrences. No discrepancy was observed with respect to ER content between primary tumors and their metastases.

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