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Case Reports
. 2019 Jan;474(1):117-123.
doi: 10.1007/s00428-018-2451-9. Epub 2018 Sep 7.

Primary classic Hodgkin lymphoma of the ileum and Epstein-Barr virus mucocutaneous ulcer of the colon: two entities compared

Magda Zanelli  1 , Maria Cecilia Mengoli  2 , Riccardo Valli  1 , Elisabetta Froio  1 , Alessandra Bisagni  1 , Maurizio Zizzo  3   4 , Loredana De Marco  1 , Stefano Ascani  5
Affiliations
Case Reports

Primary classic Hodgkin lymphoma of the ileum and Epstein-Barr virus mucocutaneous ulcer of the colon: two entities compared

Magda Zanelli et al. Virchows Arch. 2019 Jan.

Abstract

Primary classic Hodgkin lymphoma of the gastrointestinal tract represents a rare occurrence. A full patient's work-up is essential in order to exclude a secondary intestinal involvement. Histologically Epstein-Barr virus mucocutaneous ulcer closely resembles Hodgkin lymphoma. The differential diagnosis between these two entities is relevant, since both the therapeutic approach and the clinical behavior are different. Herein, we describe a case of primary classic Hodgkin lymphoma arising in the ileum and a case of Epstein-Barr virus mucocutaneous ulcer of the colon, focusing on the main clinicopathological differences.

Keywords: Diverticulitis; Epstein-Barr virus; Hodgkin lymphoma; Mucocutaneous; Ulcer.

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