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. 2018 Nov:469:14-22.
doi: 10.1016/j.carres.2018.08.016. Epub 2018 Aug 30.

Functionalized glycolipids for potential bioconjugation of vesicles

Mojtaba Tabandeh  1 , Ean Wai Goh  1 , Abbas Abdulameer Salman  2 , Thorsten Heidelberg  3 , Rusnah Syahila Duali Hussen  1
Affiliations

Functionalized glycolipids for potential bioconjugation of vesicles

Mojtaba Tabandeh et al. Carbohydr Res. 2018 Nov.

Abstract

Two azide-terminated oligoethylene oxide spacered glycolipids have been synthesized, and their assembly behavior has been studied in comparison to the corresponding base surfactants. The results suggest potential of the Guerbet lactoside-based compound for targeted drug delivery, while a coiling of the ethylene oxide linker disfavors the application of the glucoside.

Keywords: Biantennary glycolipid; CLICK chemistry coupling; Ethylene oxide spacer; Surfactant assembly; Targeted drug delivery; Vesicle bioconjugation.

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