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Case Reports
. 2019 Mar;66(1):66-69.
doi: 10.1002/jmrs.304. Epub 2018 Sep 9.

Radiotherapy for parotid IgG4-related disease

Daniel E Roos  1 , Marcus V Dreosti  2 , Craig L James  3 , Pravin Hissaria  4
Affiliations
Case Reports

Radiotherapy for parotid IgG4-related disease

Daniel E Roos et al. J Med Radiat Sci. 2019 Mar.

Abstract

We describe the use of radiotherapy for parotid IgG4-related disease (IgG4-RD), initially misdiagnosed as Kimura's disease, with sustained good partial response in a 37-year-old male. To the best of our knowledge, this is the first reported case of radiation for extra-orbital IgG4-RD, albeit inadvertently.

Keywords: IgG4-related disease; Kimura's disease; corticosteroids; parotid; radiotherapy.

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Conflict of interest statement

The authors declare no conflict of interest.

Figures

Figure 1
Figure 1
High‐power photomicrograph of left parotid biopsy (H and E × 200), showing a diffuse polymorphous inflammatory infiltrate of lymphocytes, histiocytes, eosinophils and plasma cells, together with focal stromal hyaline fibrosis.
Figure 2
Figure 2
Before and 3 months after radiotherapy demonstrating excellent clinical response.
Figure 3
Figure 3
Axial planning CT showing diffuse infiltration of the left parotid and subcutaneous soft tissues (anatomical distortion due to rotated head position for electron treatment).
See this image and copyright information in PMC

References

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