Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1986 Oct;168(1):440-3.
doi: 10.1128/jb.168.1.440-443.1986.

Requirement of the Escherichia coli dnaA gene product for plasmid F maintenance

B C Kline, T Kogoma, J E Tam, M S Shields

Requirement of the Escherichia coli dnaA gene product for plasmid F maintenance

B C Kline et al. J Bacteriol. 1986 Oct.

Abstract

There are DnaA protein-binding sites in at least one F origin of replication, and only potentially leaky dnaA(Ts) mutations had ever been used in previous studies indicating that F replication was independent of the dnaA gene product. Here we show that an Escherichia coli dnaA::Tn10 host which does not make a dnaA gene product cannot sustain autonomous or integrated F plasmid maintenance.

PubMed Disclaimer

References

    1. Mol Gen Genet. 1970;109(2):107-22 - PubMed
    1. Proc Natl Acad Sci U S A. 1983 Oct;80(19):5817-21 - PubMed
    1. Mol Gen Genet. 1971;113(3):273-84 - PubMed
    1. Bacteriol Rev. 1972 Dec;36(4):587-607 - PubMed
    1. J Bacteriol. 1974 Sep;119(3):1072-4 - PubMed

Publication types

Substances

LinkOut - more resources