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Review
. 2018 Jul-Sep;9(3):247-253.
doi: 10.1016/j.jcot.2018.07.008. Epub 2018 Jul 17.

Meniscal repair and regeneration: Current strategies and future perspectives

Kazunori Shimomura  1 , Shuichi Hamamoto  1 , David A Hart  2 , Hideki Yoshikawa  1 , Norimasa Nakamura  1   3   4
Affiliations
Review

Meniscal repair and regeneration: Current strategies and future perspectives

Kazunori Shimomura et al. J Clin Orthop Trauma. 2018 Jul-Sep.

Erratum in

  • Erratum regarding previously published articles.
    [No authors listed] [No authors listed] J Clin Orthop Trauma. 2020 Nov-Dec;11(6):1169-1171. doi: 10.1016/j.jcot.2020.09.032. Epub 2020 Sep 26. J Clin Orthop Trauma. 2020. PMID: 33013141 Free PMC article.

Abstract

The management of meniscal injuries remains difficult and challenging. Although several clinical options exist for the treatment of such injuries, complete regeneration of the damaged meniscus has proved difficult due to the limited healing capacity of the tissue. With the advancements in tissue engineering and cell-based technologies, new therapeutic options for patients with currently incurable meniscal lesions now potentially exist. This review will discuss basic anatomy, current repair techniques and treatment options for loss of meniscal integrity. Specifically, we focus on the possibility and feasibility of the latest tissue engineering approaches, including 3D printing technologies. Therefore, this discussion will facilitate a better understanding of the latest trends in meniscal repair and regeneration, and contribute to the future application of such clinical therapies for patients with meniscal injuries.

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Figures

Fig. 1
Fig. 1
Schematic representation of the fabrication of an order-made bioactive meniscal implant in 3D bioprinter.
See this image and copyright information in PMC

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