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Review
. 2016 Jan 13;10(1):17-20.
doi: 10.1177/1559827615609050. eCollection 2016 Jan-Feb.

Potentially Driver-Impairing Medications: Risks and Strategies for Injury Prevention

Timothy Ivers  1 , Nicole D White  1
Affiliations
Review

Potentially Driver-Impairing Medications: Risks and Strategies for Injury Prevention

Timothy Ivers et al. Am J Lifestyle Med. .

Abstract

Impaired driving is a major cause of motor vehicle accidents, injury, and fatality. Several classes of medication have been found to affect a driver's cognition, judgment, and reaction time and may put patients at increased risk for accidents and injury. This article will explore medications with side effects posing a potential threat to drivers, including anxiolytics, sedative hypnotics, antihistamines, and antidepressants, as well as describe potential strategies for mitigating or minimizing such risks.

Keywords: antidepressants; antihistamines; benzodiazepines; driver impairment; motor vehicle accidents; sedative hypnotics.

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References

    1. Leroy A, Morse MM; for the US Department of Transportation/National Highway Traffic Safety Administration. Exploratory Study of the Relationship Between Multiple Medications and Vehicle Crashes: Analysis of Databases. Washington, DC: U.S. DOT/NHTSA; 2008. Publication DTNH22-02-C-05075.
    1. Lococo K, Tyree R. Potentially driver-impairing prescription medications. http://www.medscape.org/viewarticle/725019. Accessed September 1, 2015.
    1. Xanax XR CIV [prescribing information]. New York, NY: Pfizer; 2005. http://www.pfizer.com/files/products/uspi_xanax_xr.pdf. Accessed September 1, 2015.
    1. Dassanayake T, Michie P, Carter G, Jones A. Effects of benzodiazepines, antidepressants and opioids on driving: a systematic review and meta-analysis of epidemiological and experimental evidence. Drug Saf. 2011;34:125-156. - PubMed
    1. Smink BE, Egberts AC, Klaas J, et al. The relationship between benzodiazepine use and traffic accidents. CNS Drugs. 2010;24:639-653. - PubMed

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