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Review
. 2018 Jul 8;10(7):e2941.
doi: 10.7759/cureus.2941.

Breast Cancer During Pregnancy

Affiliations
Review

Breast Cancer During Pregnancy

Sajid Durrani et al. Cureus. .

Abstract

Breast cancer remains the most common cancer in women. A diagnosis of cancer during pregnancy is uncommon. In recent decades, obstetricians are seeing an increasing number of women who become pregnant or desire to become pregnant after breast cancer treatment because of a delay in childbearing for a variety of reasons, including cultural, educational, and professional. Consequently, breast cancer in young women often occurs before the completion of reproductive plans. A discussion among the patient, the oncologist, and the obstetrician on the relative benefits of early delivery followed by treatment versus commencement of therapy while continuing the pregnancy is of utmost importance in order to reach a consensual decision. The best available evidence suggests that pregnancy after breast cancer increases the risk of recurrence. The birth outcome in women with a history of breast cancer is no different from that in the normal female population; however, increased risks of delivery complications have been reported in the literature. As concurrent pregnancy and breast cancer are uncommon, there are no data from large randomized trials; hence, recommendations are mainly based on retrospective studies.

Keywords: breast cancer; breast cancer diagnosis; breast cancer treatment; pregnancy.

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Conflict of interest statement

The authors have declared that no competing interests exist.

References

    1. Breast carcinoma in pregnant women. Assessment of clinicopathologic and immunohistochemical features. Middleton LP, Amin M, Gwyn K, et al. Cancer. 2003;98:1055–1060. - PubMed
    1. Breast cancer in pregnancy: a literature review. Woo JC, Yu T, Hurd TC. Arch Surg. 2003;138:91–98. - PubMed
    1. Maternal and fetal outcome after breast cancer in pregnancy. Zemlickis D, Lishner M, Degendorfer P, et al. Am J Obstet Gynecol. 1992;166:781–787. - PubMed
    1. Clinical and biologic prognostic factors in breast cancer diagnosed during postmenopausal hormone replacement therapy. Bonnier P, Romain S, Giacalone PL, et al. Obstet Gynecol. 1995;85:11–17. - PubMed
    1. Factors influencing the prognostic role of oestrogen and progesterone receptor levels in breast cancer—results of the analysis of 670 patients with 11 years of follow-up. Costa SD, Lange S, Klinga K, et al. Eur J Cancer. 2002;38:1329–1334. - PubMed

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