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. 1977 Sep 2;197(4307):999-1001.
doi: 10.1126/science.302032.

Induction of suppressor T cells in systemic lupus erythematosus by thymosin and cultured thymic epithelium

S Horowitz, W Borcherding, A V Moorthy, R Chesney, H Schulte-Wisserman, R Hong

Induction of suppressor T cells in systemic lupus erythematosus by thymosin and cultured thymic epithelium

S Horowitz et al. Science. .

Abstract

Patients with systemic lupus erythematosus lacked suppressor T cell function. Suppressor cell activity was induced in cells from many of these patients by incubation with thymosin or cultured thymic epithelium. These results suggest that thymic manipulation may be a useful therapeutic modality in this disease.

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