Induction of taurine responsiveness in Xenopus oocytes by messenger RNA from mouse brain
- PMID: 3020479
- DOI: 10.1016/0304-3940(86)90488-x
Induction of taurine responsiveness in Xenopus oocytes by messenger RNA from mouse brain
Abstract
A taurine response was induced in the surface membrane of the oocytes of Xenopus laevis by injection of the mRNA from the neonatal mouse brain, and the response was studied electrophysiologically. The permeability of mRNA-injected oocytes to chloride ions was increased by the application of taurine in a dose-dependent manner. The same oocyte also responded to GABA, but bicuculline suppressed only the GABA response. These results suggest a possibility that taurine could be a neurotransmitter of certain neurons as yet unknown in the central nervous system.
Similar articles
-
Taurine and beta-alanine act on both GABA and glycine receptors in Xenopus oocyte injected with mouse brain messenger RNA.Brain Res. 1988 Sep;464(2):97-105. doi: 10.1016/0169-328x(88)90002-2. Brain Res. 1988. PMID: 2464409
-
Taurine modulates glycine response in Xenopus oocytes injected with messenger RNA from mouse brain.Brain Res. 1988 Nov;464(3):243-6. doi: 10.1016/0169-328x(88)90030-7. Brain Res. 1988. PMID: 2850085
-
Responses to GABA, glycine and beta-alanine induced in Xenopus oocytes by messenger RNA from chick and rat brain.Proc R Soc Lond B Biol Sci. 1988 Mar 22;233(1271):201-16. doi: 10.1098/rspb.1988.0019. Proc R Soc Lond B Biol Sci. 1988. PMID: 2898147
-
The use of Xenopus oocytes to probe synaptic communication.Trends Neurosci. 1988 Jun;11(6):250-6. doi: 10.1016/0166-2236(88)90102-6. Trends Neurosci. 1988. PMID: 2465619 Review. No abstract available.
-
Development and application of caged ligands for neurotransmitter receptors in transient kinetic and neuronal circuit mapping studies.Methods Enzymol. 1998;291:443-73. doi: 10.1016/s0076-6879(98)91028-x. Methods Enzymol. 1998. PMID: 9661164 Review. No abstract available.
Cited by
-
Effect of ICV taurine on the impairment of learning, convulsions and death caused by hypoxia.Psychopharmacology (Berl). 1989;98(3):316-20. doi: 10.1007/BF00451681. Psychopharmacology (Berl). 1989. PMID: 2501810
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources