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. 1977 Aug;33(2):88-92.
doi: 10.1111/j.1423-0410.1977.tb02238.x.

Clinical and immunological studies on healthy blood donors hepatitis B antibody carriers

J Cianciara, H Swiderska, J Slusarczyk, T Loch

Clinical and immunological studies on healthy blood donors hepatitis B antibody carriers

J Cianciara et al. Vox Sang. 1977 Aug.

Abstract

Ten healthy blood donors persistently seropositive for anti-HBs and without a history of clinically overt viral hepatitis were studied. While physical examination and biochemical liver function tests exhibited normal values in all cases, immunologic studies revealed coexistence of a long-term anti-HBs carrier state with the presence of cell-mediated immunity to HBV antigens and autoantibodies in some. These results suggest a complex immunologic phenomenon underlying the development of the anti-HBs carrier state.

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