Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Case Reports
. 2018 Sep 10;4(3):e164-e166.
doi: 10.1055/s-0038-1669991. eCollection 2018 Jul.

Olfactory Nerve Schwannoma: A Case Report and Review of the Literature

Mahmoud M Taha  1 , Amr AlBakry  1 , Magdy ElSheikh  1 , Tarek H AbdelBary  1
Affiliations
Case Reports

Olfactory Nerve Schwannoma: A Case Report and Review of the Literature

Mahmoud M Taha et al. Surg J (N Y). .

Abstract

Schwannomas are benign tumors, which arise from the Schwann cells of the central or peripheral nerves. They form 8% of all intracranial tumors and most of the cases arise from vestibular division of the 8 th cranial nerve. Rare cases are shown to arise from the olfactory or optic nerve, being devoid of myelin sheath. Up to date and according to our best of knowledge, 66 cases have been reported till now. Here we present a review of the literature and a case report of a 56-year-old male with an accidently discovered anterior cranial fossa schwannoma, following a road traffic accident. Tumor was completely excised, using a right frontal approach. Histopathology revealed Antoni-A cellular pattern. Although rare, but olfactory nerve schwannomas should be included in the differential diagnosis in anterior cranial fossa space occupying lesions, and the approach should be designed taking into consideration, this rare entity.

Keywords: anterior cranial fossa schwannoma; olfactory; olfactory groove schwannoma; olfactory nerve Schwannoma; schwannoma.

PubMed Disclaimer

Conflict of interest statement

Conflict of Interest None.

Figures

Fig. 1
Fig. 1
Postcontrast computed tomography (CT) scan, showing an intra-axial right frontal space-occupying lesion.
Fig. 2
Fig. 2
Histopathological examination, showing Antoni type-A cellular pattern.
Fig. 3
Fig. 3
Postoperative noncontrast computed tomography (CT) scan, showing complete excision of the tumor.
See this image and copyright information in PMC

References

    1. Esquivel-Miranda M, De la O Ríos E, Vargas-Valenciano E, Moreno-Medina E. [Anterior skull-base schwannoma] Neurocirugia (Astur) 2017;28(06):298–305. - PubMed
    1. Figueiredo E G, Soga Y, Amorim R L, Oliveira A M, Teixeira M J. The puzzling olfactory groove schwannoma: a systematic review. Skull Base. 2011;21(01):31–36. - PMC - PubMed
    1. Manto A, Manzo G, De Gennaro A, Martino V, Buono V, Serino A. An enigmatic clinical entity: A new case of olfactory schwannoma. Neuroradiol J. 2016;29(03):174–178. - PMC - PubMed
    1. Figueroa-Angel V, Rodríguez-Aceves C A, Calderon-Miranda W G, Escobar-Hernandez N, Joaquim A F, Moscote-Salazar L R. Subfrontal schwannoma: case report and review of literature. World Neurosurg. 2017;111:386–390. - PubMed
    1. Quick J, Hattingen E, Delbridge C, Seifert V, Marquardt G. Schwannoma of the olfactory nerve. Report of two cases and review of the literature. Clin Neurol Neurosurg. 2015;132:44–46. - PubMed

Publication types