Treatment satisfaction in women receiving palbociclib combination therapies for advanced/metastatic breast cancer

Abstract

Aim: To understand treatment satisfaction in patients with advanced or metastatic breast cancer receiving palbociclib plus an aromatase inhibitor or palbociclib plus fulvestrant in a real-world setting.

Patients & methods: We performed an observational, cross-sectional, web-based survey of 604 patients with self-reported hormone receptor-positive (HR+)/HER2-negative (HER2-) ABC/mBC in six countries.

Results: Overall, more than 96% of patients reported the benefits of their palbociclib combination therapy met or exceeded their expectations. Patient expectations and satisfaction with therapy did not differ between patients on palbociclib plus letrozole and palbociclib plus fulvestrant, or between patients with visceral and nonvisceral metastases.

Conclusion: The patients on palbociclib combination therapy reported high satisfaction scores across multiple countries.

Keywords: CDK4/6; advanced breast cancer; aromatase inhibitors; estrogen receptor antagonist; fulvestrant; hormone receptor-positive; letrozole; metastatic breast cancer; palbociclib; patient satisfaction.