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. 2018 Aug;34(4):167-174.
doi: 10.3393/ac.2018.08.02. Epub 2018 Aug 31.

Intersphincteric Resection for Patients With Low-Lying Rectal Cancer: Oncological and Functional Outcomes

In Ja Park  1 , Jin Cheon Kim  1
Affiliations

Intersphincteric Resection for Patients With Low-Lying Rectal Cancer: Oncological and Functional Outcomes

In Ja Park et al. Ann Coloproctol. 2018 Aug.

Abstract

The aim of this review is to evaluate the outcomes after an intersphincteric resection (ISR) for patients with low-lying rectal cancer. Reports published in the literature regarding surgical, oncological, and functional outcomes of an ISR were reviewed. The morbidity after an ISR was 7.7%-32%, and anastomotic leakage was the most common adverse event. Local recurrence rates ranged from 0% to 12%, 5-year overall survival rates ranged from 62% to 92%, and rates of major incontinence ranged from 0% to 25.8% after an ISR. An ISR is a safe procedure for sphincter-saving rectal surgery in patients with very low rectal cancer; it does not compromise the oncological outcomes of the resection and is a valuable alternative to an abdominoperineal resection. While the functional outcomes after an ISR were found to be acceptable, the long-term functional outcome and quality of life still require careful investigation. ISRs have been performed with surgical and oncologic safety on patients with low-lying rectal cancer. However, patients must be selected very carefully for an ISR, considering the associated functional derangement and the limited extent of the resection.

Keywords: Functional outcome; Intersphincteric resection; Low-lying rectal cancer; Oncologic outcome.

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Conflict of interest statement

No potential conflict of interest relevant to this article was reported.

References

    1. Cohen Z, Myers E, Langer B, Taylor B, Railton RH, Jamieson C. Double stapling technique for low anterior resection. Dis Colon Rectum. 1983;26:231–5. - PubMed
    1. Baran JJ, Goldstein SD, Resnik AM. The double-staple technique in colorectal anastomoses: a critical review. Am Surg. 1992;58:270–2. - PubMed
    1. Heald RJ. Rectal cancer in the twenty-first century-radical operations anterior resection (AR) and abdomino-perineal excision (APE) In: Fisher JE, Bland KI, editors. Mastery of surgery. Philadelphia (PA): Lippincott-Raven; 2007. pp. 1542–55.
    1. Heald RJ, Moran BJ, Ryall RD, Sexton R, MacFarlane JK. Rectal cancer: the Basingstoke experience of total mesorectal excision, 1978-1997. Arch Surg. 1998;133:894–9. - PubMed
    1. Pollett WG, Nicholls RJ. The relationship between the extent of distal clearance and survival and local recurrence rates after curative anterior resection for carcinoma of the rectum. Ann Surg. 1983;198:159–63. - PMC - PubMed

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