Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Editorial
. 2018 Oct;29(10):2447-2448.
doi: 10.1681/ASN.2018080846. Epub 2018 Sep 12.

Are Cyst-Associated Macrophages in Polycystic Kidney Disease the Equivalent to TAMs in Cancer?

Affiliations
Editorial

Are Cyst-Associated Macrophages in Polycystic Kidney Disease the Equivalent to TAMs in Cancer?

Thomas Weimbs. J Am Soc Nephrol. 2018 Oct.
No abstract available

Keywords: fibrosis; innate immune system; macrophages; polycystic kidney disease; renal cysts; tumor-associated macrophages.

PubMed Disclaimer

Comment on

References

    1. Lee S, Huen S, Nishio H, Nishio S, Lee HK, Choi BS, et al. : Distinct macrophage phenotypes contribute to kidney injury and repair. J Am Soc Nephrol 22: 317–326, 2011 - PMC - PubMed
    1. Weimbs T: Polycystic kidney disease and renal injury repair: Common pathways, fluid flow, and the function of polycystin-1. Am J Physiol Renal Physiol 293: F1423–F1432, 2007 - PubMed
    1. Cassini K, Kurtz S, Glazer T, Somlo S, Cantley LG: Mcp1 promotes macrophage-dependent cyst expansion in autosomal dominant polycystic kidney disease. J Am Soc Nephrol J Am Soc Nephrol 29: 2471–2481, 2018 - PMC - PubMed
    1. Karihaloo A, Koraishy F, Huen SC, Lee Y, Merrick D, Caplan MJ, et al. : Macrophages promote cyst growth in polycystic kidney disease. J Am Soc Nephrol 22: 1809–1814, 2011 - PMC - PubMed
    1. Song CJ, Zimmerman KA, Henke SJ, Yoder BK: Inflammation and fibrosis in polycystic kidney disease. Results Probl Cell Differ 60: 323–344, 2017 - PMC - PubMed

LinkOut - more resources