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Case Reports
. 2018 Jul 9;10(7):e2951.
doi: 10.7759/cureus.2951.

A Case of Isolated Gastrointestinal Histoplasmosis

Jasmine Bhinder  1 , Amit Mori  1 , Wenqing Cao  2 , Anju Malieckal  3
Affiliations
Case Reports

A Case of Isolated Gastrointestinal Histoplasmosis

Jasmine Bhinder et al. Cureus. .

Abstract

Histoplasmosis is a self-limited and asymptomatic disease in immunocompetent individuals. Patients with untreated human immunodeficiency virus (HIV) or immune suppression due to medications such as corticosteroids can present with disseminated and life-threatening infections. We present a case of a 60-year-old female that presented with recurrent diarrhea that was found to have isolated gastrointestinal (GI) histoplasmosis. The rarity of this case is due to the isolated colonic involvement and lack of respiratory symptoms (the portal of infection). In conclusion, clinicians should be aware of isolated histoplasmosis affecting the GI tract and careful endoscopic evaluation with adequate sampling is warranted to confirm the diagnosis.

Keywords: acquired immunodeficiency syndrome; disseminated histoplasmosis; intestinal histoplasmosis.

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Conflict of interest statement

The authors have declared that no competing interests exist.

Figures

Figure 1
Figure 1. Endoscopy - Isolated 5 mm ulcer in the cecum.
Figure 2
Figure 2. Histiocytosis with intracellular microorganisms within the lamina propria.
Figure 3
Figure 3. Positive periodic acid Schiff stain.
Figure 4
Figure 4. Positive Grocott's methenamine silver stain.
See this image and copyright information in PMC

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