Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2018 Aug 28:5:115.
doi: 10.3389/fcvm.2018.00115. eCollection 2018.

Mechanical Circulatory Support for Single Ventricle Failure

Massimo Griselli  1 , Raina Sinha  1 , Subin Jang  1 , Gianluigi Perri  2 , Iki Adachi  3
Affiliations
Review

Mechanical Circulatory Support for Single Ventricle Failure

Massimo Griselli et al. Front Cardiovasc Med. .

Abstract

Mechanical circulatory support (MCS) for failing single ventricle (SV) physiology is a complex and challenging problem, which has not yet been satisfactorily addressed. Advancements in surgical strategies and techniques along with intensive care management have substantially improved the outcomes of neonatal palliation for SV physiology, particularly for hypoplastic left heart syndrome (HLHS). This is associated with a steady increase in the number of SV patients who are susceptible to develop heart failure (HF) and would potentially require MCS at a certain stage in their palliation. We have reviewed the literature regarding the reported modalities of MCS use in the management of SV patients. This includes analysis of various devices and strategies used for failing circulation at distinct stages of the SV pathway: after neonatal palliation, after the superior cavo-pulmonary connection (SCPC), and after total cavo-pulmonary connection (TCPC).

Keywords: VA ECMO; fontan physiology; mechanical circulatory support; single ventricle; ventricular assist devices.

PubMed Disclaimer

Figures

Figure 1
Figure 1
Anatomy following Norwood-mBTs.
Figure 2
Figure 2
Anatomy following Norwood-mBTs with BHE as a UVAD.
Figure 3
Figure 3
Anatomy following SCPC.
Figure 4
Figure 4
Anatomy of BHE following SCPC as a UVAD.
Figure 5
Figure 5
Possible cannulation for BHE BiVAD following TCPC.
See this image and copyright information in PMC

References

    1. Fontan F, Baudet E. Surgical repair of tricuspid atresia. Thorax (1971) 26:240–8. 10.1136/thx.26.3.240 - DOI - PMC - PubMed
    1. Khairy P, Poirier N, Mercier L. Univentricular Heart. Circulation (2007) 115:800–12. 10.1161/circulationaha.105.592378 - DOI - PubMed
    1. Ghanayem NS, Berger S, Tweddell JS. Medical management of the failing Fontan. Pediatric Cardiol. (2007) 28:465–71. 10.1007/s00246-007-9007-0 - DOI - PubMed
    1. Stanford W, Armstrong RG, Cline RE, King TD. Right atrium-pulmonary artery allograft for correction of tricuspid atresia. J Thorac Cardiovasc Surg. (1973) 66:105–11. - PubMed
    1. Kreutzer GO, Vargas FJ, Schlichter AJ, Laura JP, Suarez JC, Coronel AR, et al. . Atriopulmonary anastomosis. J Thorac Cardiovasc Surg. (1982) 83:427–36. - PubMed