Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Sentinel Surveillance for Congenital Rubella Syndrome - India, 2016-2017

Manoj Murhekar et al. MMWR Morb Mortal Wkly Rep. .

Abstract

Rubella infection during pregnancy can result in miscarriage, fetal death, stillbirth, or a constellation of congenital malformations known as congenital rubella syndrome (CRS). The 11 countries in the World Health Organization (WHO) South-East Asia Region are committed to the elimination of measles and control of rubella and CRS by 2020. Until 2016, when the Government of India's Ministry of Health and Family Welfare and the Indian Council of Medical Research initiated surveillance for CRS in five sentinel sites, India did not conduct systematic surveillance for CRS. During the first 8 months of surveillance, 207 patients with suspected CRS were identified. Based on clinical details and serologic investigations, 72 (34.8%) cases were classified as laboratory-confirmed CRS, four (1.9%) as congenital rubella infection, 11 (5.3%) as clinically compatible cases, and 120 (58.0%) were excluded as noncases. The experience gained during the first phase of surveillance will be useful in expanding the surveillance network, and data from the surveillance network will be used to help monitor progress toward control of rubella and CRS in India.

PubMed Disclaimer

Conflict of interest statement

All authors have completed and submitted the ICMJE form for disclosure of potential conflicts of interest. No potential conflicts of interest were disclosed.

References

    1. Lambert N, Strebel P, Orenstein W, Icenogle J, Poland GA. Rubella. Lancet 2015;385:2297–307. 10.1016/S0140-6736(14)60539-0 - DOI - PMC - PubMed
    1. Banatvala JE, Brown DW. Rubella. Lancet 2004;363:1127–37. 10.1016/S0140-6736(04)15897-2 - DOI - PubMed
    1. World Health Organization. Strategic plan for measles elimination and rubella and congenital rubella syndrome control in the South-East Asia Region. New Delhi, India: World Health Organization Regional Office for South-East Asia; 2015. http://www.searo.who.int/immunization/documents/sear_mr_strategic_plan_2...
    1. World Health Organization India. India launches one of the world’s largest vaccination campaigns against measles and rubella syndrome with WHO support. New Delhi, India: World Health Organization Regional Office for South-East Asia; 2017. http://www.searo.who.int/india/mediacentre/events/2017/Measles_Rubella/en
    1. Government of India Ministry of Health and Family Welfare. Field guide: measles surveillance & outbreak investigation. New Delhi, India: Government of India Ministry of Health and Family Welfare; 2005. http://www.searo.who.int/india/topics/measles/Measles_surveillance_and_o...