Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2018 Sep;97(37):e12390.
doi: 10.1097/MD.0000000000012390.

Recent global trends in testicular cancer incidence and mortality

Jee Soo Park  1 , Jongchan Kim, Ahmed Elghiaty, Won Sik Ham
Affiliations

Recent global trends in testicular cancer incidence and mortality

Jee Soo Park et al. Medicine (Baltimore). 2018 Sep.

Abstract

Testicular cancer (TCa) has a relatively rare incidence and mortality, but has not been thoroughly evaluated. We analyzed global variations and recent trends in TCa incidence and mortality.Age-standardized rates (ASRs) of TCa incidence and mortality were retrieved from the GLOBOCAN 2012 database. Temporal patterns were assessed using data obtained from the Cancer Incidence in Five Continents (volumes I-X) and World Health Organization Mortality databases. The incidence and mortality trends over the last 10 years were analyzed using join point analysis.Western and Northern Europe had the highest incidence of TCa (ASR = 8.7 and 7.2, respectively), with most countries showing an increase in incidence rates except for China, which had a stable incidence. Incidence rates were markedly increased in Southern European countries (average annual percent change of 6.8% in Croatia and 6.1% in Spain) but were attenuated in western Europe. The highest mortality rates were observed in western Asia (ASR = 0.7), with most countries showing a decrease in mortality.While the incidence of TCa has increased, mortality from TCa has decreased in most countries. More socioeconomically developed countries had a higher incidence of TCa with lower mortality.

PubMed Disclaimer

Conflict of interest statement

None of the authors have any conflicts of interest to declare.

Figures

Figure 1
Figure 1
International variations in estimates of national age-standardized incidence (A) and mortality rates (B) of testicular cancer in all age groups. [18]
Figure 2
Figure 2
Trends in age-standardized (world) incidence and mortality rates of testicular cancer in all age groups. Dots are observed values; solid lines are locally weighted regression curves (30% of the data were used in smoothing each point). [19,21]
Figure 2 (Continued)
Figure 2 (Continued)
Trends in age-standardized (world) incidence and mortality rates of testicular cancer in all age groups. Dots are observed values; solid lines are locally weighted regression curves (30% of the data were used in smoothing each point). [19,21]
Figure 3
Figure 3
Average annual percent change in testicular cancer (A) incidence and (B) mortality rates for the last 10 years of available data by region in all age groups.
Figure 3 (Continued)
Figure 3 (Continued)
Average annual percent change in testicular cancer (A) incidence and (B) mortality rates for the last 10 years of available data by region in all age groups.
See this image and copyright information in PMC

References

    1. Bosl GJ, Motzer RJ. Testicular germ-cell cancer. N Engl J Med 1997;337:242. - PubMed
    1. Oliver RT. Testis cancer. Curr Opin Oncol 1997;9:287. - PubMed
    1. Ferlay J, Shin H, Bray F, et al. GLOBOCAN 2008 v2.0, Cancer Incidence and Mortality Worldwide. IARC Cancer Base No 10. Lyon, France: International Agency for Research on Cancer; 2010.
    1. Chia VM, Quraishi SM, Devesa SS, et al. International trends in the incidence of testicular cancer 1973–2002. Cancer Epidemiol Biomarkers Prev 2010;19:1151–9. - PMC - PubMed
    1. Huyghe E, Matsuda T, Thonneau P. Increasing incidence of testicular cancer worldwide: a review. J Urol 2003;170:5–11. - PubMed