Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2018 Oct;27(4):675-684.
doi: 10.1016/j.soc.2018.05.008. Epub 2018 Jul 21.

Health-Related Quality of Life: The Impact on Morbidity and Mortality

Andrea Sitlinger  1 , Syed Yousuf Zafar  2
Affiliations
Review

Health-Related Quality of Life: The Impact on Morbidity and Mortality

Andrea Sitlinger et al. Surg Oncol Clin N Am. 2018 Oct.

Abstract

In the age of ever-expanding treatments and precision medicine, the hope for cure remains the ultimate goal for patients and providers. Equally important to many patients is the quality of life achieved during and after treatment. Evidence suggests that overall quality of life is important to patients and plays a role in determining outcomes in patients with cancer. This article examines components of health-related quality of life and cancer treatment, including physical, psychosocial, and financial burden, as well as how these components affect patients' overall wellbeing and survival.

Keywords: Financial burden; Health-related quality of life; Physical symptom burden; Psychosocial symptom burden.

PubMed Disclaimer

References

    1. Cella DF. Measuring quality of life in palliative care. Semin Oncol 1995;22(2 Suppl 3):73–81. - PubMed
    1. Guidance for industry patient-reported outcome measures: use in medical product development to support labeling claims. US Food and Drug Administration; 2009. - PMC - PubMed
    1. Quinten C, et al. Baseline quality of life as a prognostic indicator of survival: a meta-analysis of individual patient data from EORTC clinical trials. Lancet Oncol 2009;10(9):865–71. - PubMed
    1. Epplein M, et al. Quality of life after breast cancer diagnosis and survival. J Clin Oncol 2011;29(4):406–12. - PMC - PubMed
    1. Osthus AA, et al. Health-related quality of life scores in long-term head and neck cancer survivors predict subsequent survival: a prospective cohort study. Clin Otolaryngol 2011;36(4):361–8. - PubMed