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Comment
. 2018 Dec;34(12):1015-1016.
doi: 10.1016/j.pt.2018.08.010. Epub 2018 Sep 10.

New Evidence for Hypnozoite-Independent Plasmodium vivax Malarial Recurrences

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Comment

New Evidence for Hypnozoite-Independent Plasmodium vivax Malarial Recurrences

Miles B Markus. Trends Parasitol. 2018 Dec.

Abstract

Information provided in recent, related papers has wide-ranging implications concerning, inter alia, the transmission of malaria, drug treatment, and eradication of the disease. Additionally, the research results represent support for the idea that recurrences of Plasmodium vivax malaria can arise from both liver hypnozoites and extravascular merozoites in bone marrow.

Keywords: bone marrow; life cycle; liver; recrudescence; relapse; spleen.

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