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Comment
. 2018 Oct;15(10):582.
doi: 10.1038/s41575-018-0068-8.

Senescence prevents regeneration after acute liver injury

Hugh Thomas  1
Affiliations
Comment

Senescence prevents regeneration after acute liver injury

Hugh Thomas. Nat Rev Gastroenterol Hepatol. 2018 Oct.
No abstract available

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Comment on

  • TGFβ inhibition restores a regenerative response in acute liver injury by suppressing paracrine senescence.
    Bird TG, Müller M, Boulter L, Vincent DF, Ridgway RA, Lopez-Guadamillas E, Lu WY, Jamieson T, Govaere O, Campbell AD, Ferreira-Gonzalez S, Cole AM, Hay T, Simpson KJ, Clark W, Hedley A, Clarke M, Gentaz P, Nixon C, Bryce S, Kiourtis C, Sprangers J, Nibbs RJB, Van Rooijen N, Bartholin L, McGreal SR, Apte U, Barry ST, Iredale JP, Clarke AR, Serrano M, Roskams TA, Sansom OJ, Forbes SJ. Bird TG, et al. Sci Transl Med. 2018 Aug 15;10(454):eaan1230. doi: 10.1126/scitranslmed.aan1230. Sci Transl Med. 2018. PMID: 30111642 Free PMC article.

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