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Case Reports
. 1977 Jun;28(3):433-6.

Detection and characterization of DNA-anti-DNA complexes in a patient with systemic lupus erythematosus

C D Bruneau, J P Edmonds, G R Hughes, L Aarden
Case Reports

Detection and characterization of DNA-anti-DNA complexes in a patient with systemic lupus erythematosus

C D Bruneau et al. Clin Exp Immunol. 1977 Jun.

Abstract

DNase digestion of SLE serum, with consequent release of bound DNA antibody has been proposed as a method for the direct demonstration of circulating DNA-anti-DNA complexes. In the present studies on the serum of a girl with active SLE nephritis, circulating DNA-anti-DNA complexes were demonstrated at the precise time of relapse of SLE nephritis. Ultracentrifugation showed that these complexes were of low molecular weight.

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References

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