A FRESH approach: Combining basic science and social good

Thumbi Ndung'u^{1

2

3

4}, Krista L Dong^{1

2

3

4}, Douglas S Kwon^{1

2

3

4}, Bruce D Walker^{1

2

3

4}

Affiliations

¹ Thumbi Ndung'u is a professor and the scientific director of the HIV Pathogenesis Programme and Doris Duke Medical Research Institute, University of KwaZulu-Natal (UKZN), and an investigator at the Africa Health Research Institute, Durban 4001, South Africa; an investigator at the Ragon Institute of Massachusetts General Hospital (MGH), Massachusetts Institute of Technology (MIT), and Harvard, Cambridge, MA 02139, USA; and a group leader at the Max Planck Institute for Infection Biology, Berlin, Germany.
² Krista L. Dong is a lecturer at Harvard Medical School; an assistant in Immunology at the Ragon Institute of MGH, MIT, and Harvard University, Cambridge, MA 02139, USA; and a lecturer in the Infectious Disease Division, Massachusetts General Hospital, Boston, MA 02114, USA.
³ Douglas S. Kwon is an assistant professor at Harvard Medical School, Boston MA 021145, USA; a group leader at the Ragon Institute of MGH, MIT and Harvard University, Cambridge, MA 02139, USA; and an associate physician in the Infectious Disease Division, MGH, Boston, MA 02114, USA.
⁴ Bruce D. Walker is the director of the Ragon Institute of MGH, MIT, and Harvard University, Cambridge, MA 02139, USA; an adjunct professor at the HIV Pathogenesis Programme and the Doris Duke Medical Research Institute, UKZN, and an associate of the Center for the AIDS Programme of Research in South Africa (CAPRISA), Durban 4001, South Africa; a physician in the Infectious Disease Division, MGH, Boston, MA 02114, USA; a professor in the Institute for Medical Sciences and Engineering, MIT, Cambridge, MA 02139, USA; and an investigator of the Howard Hughes Medical Institute, Chevy Chase, MD 20815, USA. Email: bwalker@mgh.harvard.edu.

PMID: 30217812
PMCID: PMC7593829
DOI: 10.1126/sciimmunol.aau2798

Editorial

A FRESH approach: Combining basic science and social good

Thumbi Ndung'u et al. Sci Immunol. 2018.

. 2018 Sep 14;3(27):eaau2798.

doi: 10.1126/sciimmunol.aau2798.

Authors

Thumbi Ndung'u^{1

2

3

4}, Krista L Dong^{1

2

3

4}, Douglas S Kwon^{1

2

3

4}, Bruce D Walker^{1

2

3

4}

Affiliations

¹ Thumbi Ndung'u is a professor and the scientific director of the HIV Pathogenesis Programme and Doris Duke Medical Research Institute, University of KwaZulu-Natal (UKZN), and an investigator at the Africa Health Research Institute, Durban 4001, South Africa; an investigator at the Ragon Institute of Massachusetts General Hospital (MGH), Massachusetts Institute of Technology (MIT), and Harvard, Cambridge, MA 02139, USA; and a group leader at the Max Planck Institute for Infection Biology, Berlin, Germany.
² Krista L. Dong is a lecturer at Harvard Medical School; an assistant in Immunology at the Ragon Institute of MGH, MIT, and Harvard University, Cambridge, MA 02139, USA; and a lecturer in the Infectious Disease Division, Massachusetts General Hospital, Boston, MA 02114, USA.
³ Douglas S. Kwon is an assistant professor at Harvard Medical School, Boston MA 021145, USA; a group leader at the Ragon Institute of MGH, MIT and Harvard University, Cambridge, MA 02139, USA; and an associate physician in the Infectious Disease Division, MGH, Boston, MA 02114, USA.
⁴ Bruce D. Walker is the director of the Ragon Institute of MGH, MIT, and Harvard University, Cambridge, MA 02139, USA; an adjunct professor at the HIV Pathogenesis Programme and the Doris Duke Medical Research Institute, UKZN, and an associate of the Center for the AIDS Programme of Research in South Africa (CAPRISA), Durban 4001, South Africa; a physician in the Infectious Disease Division, MGH, Boston, MA 02114, USA; a professor in the Institute for Medical Sciences and Engineering, MIT, Cambridge, MA 02139, USA; and an investigator of the Howard Hughes Medical Institute, Chevy Chase, MD 20815, USA. Email: bwalker@mgh.harvard.edu.

PMID: 30217812
PMCID: PMC7593829
DOI: 10.1126/sciimmunol.aau2798

Abstract

A program to study HIV infection is empowering African women.

PubMed Disclaimer

References

1. Dong KL, Moodley A, Kwon DS, Ghebremichael MS, Dong M, Ismail N, Ndhlovu ZM, Mabuka JMds, Muema DM, Pretorius K, Lin N, Walker BD, Ndung’u T. Detection and treatment of Fiebig stage I HIV-1 infection in young at-risk women in South Africa: a prospective cohort study. Lancet HIV. 2018;5(1):e35–e44. - PMC - PubMed
1. Anahtar MN, Byrne EH, Doherty KE, Bowman BA, Yamamoto HS, Soumillon M, Padavattan N, Ismail N, Moodley A, Sabatini ME, Ghebremichael MS, Nusbaum C, Huttenhower C, Virgin HW, Ndung’u T, Dong KL, Walker BD, Fichorova RN, Kwon DS. Cervicovaginal bacteria are a major modulator of host inflammatory responses in the female genital tract. Immunity. 2015;42(5):965–76. - PMC - PubMed
1. Gosmann C, Anahtar MN, Handley SA, Farcasanu M, Abu-Ali G, Bowman BA, Padavattan N, Desai C, Droit L, Moodley A, Dong M, Chen Y, Ismail N, Ndung’u T, Ghebremichael MS, Wesemann DR, Mitchell C, Dong KL, Huttenhower C, Walker BD, Virgin HW, Kwon DS. Lactobacillus-Deficient Cervicovaginal Bacterial Communities Are Associated with Increased HIV Acquisition in Young South African Women. Immunity. 2017;46(1):29–37. - PMC - PubMed
1. Byrne EH, Anahtar MN, Cohen KE, Moodley A, Padavattan N, Ismail N, Bowman BA, Olson GS, Mabhula A, Leslie A, Ndung’u T, Walker BD, Ghebremichael MS, Dong KL, Kwon DS. Association between injectable progestin-only contraceptives and HIV acquisition and HIV target cell frequency in the female genital tract in South African women: a prospective cohort study. Lancet Infect Dis. 2016;16(4):441–8. - PMC - PubMed
1. Ndhlovu ZM, Kamya P, Mewalal N, Kloverpris HN, Nkosi T, Pretorius K, Laher F, Ogunshola F, Chopera D, Shekhar K, Ghebremichael M, Ismail N, Moodley A, Malik A, Leslie A, Goulder PJ, Buus S, Chakraborty A, Dong K, Ndung’u T, Walker BD. Magnitude and Kinetics of CD8+ T Cell Activation during Hyperacute HIV Infection Impact Viral Set Point. Immunity. 2015;43(3):591–604. - PMC - PubMed

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A FRESH approach: Combining basic science and social good

Affiliations

A FRESH approach: Combining basic science and social good

Authors

Affiliations

Abstract

References

Publication types

MeSH terms

Grants and funding

LinkOut - more resources

Full Text Sources

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