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Comment
. 2018 Oct;28(10):965-966.
doi: 10.1038/s41422-018-0088-5.

Staged profiling of sperm development in sync

Navin B Ramakrishna  1   2 , M Azim Surani  3   4
Affiliations
Comment

Staged profiling of sperm development in sync

Navin B Ramakrishna et al. Cell Res. 2018 Oct.
No abstract available

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Figures

Fig. 1
Fig. 1
Profiling spermatogenesis to identify newfound regulators. a Mice at 2 dpp were treated with a Retinoic Acid (RA) synthesis inhibitor for 7 days, followed by a RA pulse at 10 dpp to stimulate the first wave of spermatogenesis. Dense time point collection sampled 20 stages of sperm development up till 32.5 dpp. Colors along the timeline represent the seven scRNA-seq t-SNE clusters obtained in the analysis. b Regulators identified in the analysis include, top: Fbxo47 in regulating recombination during meiosis, middle: transcription factor Sox30 in regulating spermatid development, bottom: cell surface marker CD63 in marking immature round spermatids
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References

    1. Amann RP. J. Androl. 2008;29:469–487. doi: 10.2164/jandrol.107.004655. - DOI - PubMed
    1. Chen Y, et al. Cell Res. 2018;28:879–896. doi: 10.1038/s41422-018-0074-y. - DOI - PMC - PubMed
    1. Clermont Y. Physiol. Rev. 1972;52:198–236. doi: 10.1152/physrev.1972.52.1.198. - DOI - PubMed
    1. Picelli S, et al. Nat. Methods. 2013;10:1096–1098. doi: 10.1038/nmeth.2639. - DOI - PubMed
    1. Lukassen S, Bosch E, Ekici AB, Winterpacht A. Sci. Rep. 2018;8:1274–1277. doi: 10.1038/s41598-018-24725-0. - DOI - PMC - PubMed

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