Umbilical cord tissue cryopreservation: a short review
- PMID: 30219095
- PMCID: PMC6138889
- DOI: 10.1186/s13287-018-0992-0
Umbilical cord tissue cryopreservation: a short review
Abstract
In this review we present current evidence on the possibility of umbilical cord tissue cryopreservation for subsequent clinical use. Protocols for obtaining umbilical cord-derived vessels, Wharton's jelly-based grafts, multipotent stromal cells, and other biomedical products from cryopreserved umbilical cords are highlighted, and their prospective clinical applications are discussed. Examination of recent literature indicates we should expect high demand for cryopreservation of umbilical cord tissues in the near future.
Keywords: Cryoprotectants; Graft; Mesenchymal stem cells; Tissue cryopreservation; Umbilical cord; Vessels.
Conflict of interest statement
Ethics approval and consent to participate
Not applicable.
Consent for publication
Not applicable.
Competing interests
The authors declare that they have no competing interests.
Publisher’s Note
Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.
Similar articles
-
DMSO- and Serum-Free Cryopreservation of Wharton's Jelly Tissue Isolated From Human Umbilical Cord.J Cell Biochem. 2016 Oct;117(10):2397-412. doi: 10.1002/jcb.25563. Epub 2016 Jun 23. J Cell Biochem. 2016. PMID: 27038129 Free PMC article.
-
A simple and serum-free protocol for cryopreservation of human umbilical cord as source of Wharton's jelly mesenchymal stem cells.Cryobiology. 2014 Jun;68(3):467-72. doi: 10.1016/j.cryobiol.2014.03.010. Epub 2014 Apr 4. Cryobiology. 2014. PMID: 24704519
-
Freezing of Fresh Wharton's Jelly From Human Umbilical Cords Yields High Post-Thaw Mesenchymal Stem Cell Numbers for Cell-Based Therapies.J Cell Biochem. 2016 Apr;117(4):815-27. doi: 10.1002/jcb.25375. Epub 2015 Sep 17. J Cell Biochem. 2016. PMID: 26365815
-
Wharton's Jelly stem cells: future clinical applications.Placenta. 2011 Oct;32 Suppl 4:S311-5. doi: 10.1016/j.placenta.2011.06.010. Epub 2011 Jul 6. Placenta. 2011. PMID: 21733573 Review.
-
Pericytes in the Umbilical Cord.Adv Exp Med Biol. 2019;1122:211-233. doi: 10.1007/978-3-030-11093-2_12. Adv Exp Med Biol. 2019. PMID: 30937871 Review.
Cited by
-
Umbilical Cord Blood Banking: An Update For Childbirth Educators.J Perinat Educ. 2022 Oct 1;31(4):199-205. doi: 10.1891/JPE-2021-0006. J Perinat Educ. 2022. PMID: 36277229 Free PMC article.
-
An In Vivo Assessment of Different Mesenchymal Stromal Cell Tissue Types and Their Differentiation State on a Shape Memory Polymer Scaffold for Bone Regeneration.J Biomed Mater Res B Appl Biomater. 2024 Dec;112(12):e35516. doi: 10.1002/jbm.b.35516. J Biomed Mater Res B Appl Biomater. 2024. PMID: 39607370
-
Temporary Storage of the Human Nasal Tissue and Cell Sheet for Wound Repair.Front Bioeng Biotechnol. 2021 Jul 21;9:687946. doi: 10.3389/fbioe.2021.687946. eCollection 2021. Front Bioeng Biotechnol. 2021. PMID: 34368095 Free PMC article.
-
Decellularized Wharton Jelly Implants Do Not Trigger Collagen and Cartilaginous Tissue Production in Tracheal Injury in Rabbits.Life (Basel). 2022 Jun 23;12(7):942. doi: 10.3390/life12070942. Life (Basel). 2022. PMID: 35888031 Free PMC article.
-
Current Status and Future Prospects of Perinatal Stem Cells.Genes (Basel). 2020 Dec 23;12(1):6. doi: 10.3390/genes12010006. Genes (Basel). 2020. PMID: 33374593 Free PMC article. Review.
References
-
- Knudtzon S. In vitro growth of granulocytic colonies from circulating cells in human cord blood. Blood. 1974;43(3):357–361. - PubMed
-
- Gluckman E, Broxmeyer HA, Auerbach AD, Friedman HS, Douglas GW, Devergie A, Esperou H, Thierry D, Socie G, Lehn P. Hematopoietic reconstitution in a patient with Fanconi’s anemia by means of umbilical-cord blood from an HLA-identical sibling. N Engl J Med. 1989;321(17):1174–1178. doi: 10.1056/NEJM198910263211707. - DOI - PubMed
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Other Literature Sources