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Review
. 2018 Nov;46(11):4791-4799.
doi: 10.1177/0300060518792444. Epub 2018 Sep 17.

Interdigitating dendritic cell sarcoma located in the groin: a case report and literature review

Hong-Tao Wang  1 , Hong-Yang Xu  1   2 , Rong Zhang  1 , Zhuo-Gang Liu  1 , Guo-Jun Zhang  1
Affiliations
Review

Interdigitating dendritic cell sarcoma located in the groin: a case report and literature review

Hong-Tao Wang et al. J Int Med Res. 2018 Nov.

Abstract

Interdigitating dendritic cell sarcoma (IDCS) is an extremely rare subtype of dendritic cell neoplasms, and current knowledge on this tumor is limited. We herein report a case of an IDCS in a 64-year-old man who presented with a right inguinal mass combined with extensive retroperitoneal, pulmonary, hepatic, renal, and bone marrow infiltration. Because of the advanced stage of the disease, we performed five cycles of chemotherapy, including cyclophosphamide, doxorubicin, vincristine, and prednisone (CHOP); doxorubicin, bleomycin, vinblastine, and dacarbazine (ABVD); and ABVD combined with cisplatin, and one cycle of radiotherapy. The patient's inguinal mass became smaller during the treatment, but there was no change in the extent of infiltration at the other sites. The patient died 8 months after the initial diagnosis. We also herein review the etiology, diagnosis, differential diagnosis, treatment, and prognosis of IDCS, and analyze the characteristics of IDCS in Chinese patients.

Keywords: Interdigitating dendritic cell sarcoma; chemotherapy; dendritic cell neoplasm; inguinal mass; prognosis; radiotherapy.

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Figures

Figure 1.
Figure 1.
Histopathologic image of the right inguinal lymph node biopsy of the 64-year-old man described in the present report (magnification: ×100).
See this image and copyright information in PMC

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