Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Case Reports
. 2018 Jan-Dec:9:2150132718799023.
doi: 10.1177/2150132718799023.

Paraneoplastic Phenomena in a Patient With Locally Destructive and Metastatic Renal Cell Carcinoma

Allen L Pimienta  1 , Thomas A Billings  1 , Robert G Fish  1
Affiliations
Case Reports

Paraneoplastic Phenomena in a Patient With Locally Destructive and Metastatic Renal Cell Carcinoma

Allen L Pimienta et al. J Prim Care Community Health. 2018 Jan-Dec.

Abstract

Renal cell carcinoma (RCC) accounts for approximately 80% of all primary renal neoplasms in United States causing approximately 65 000 new cases of RCC and 14 000 deaths each year. Symptoms of RCC typically include weight loss and night sweats but may also feature paraneoplastic phenomena in advanced stages as well as flank pain, gross hematuria, scrotal varicocele, inferior vena cava pathology, and a palpable abdominal mass. In this article, we present the course of a patient with advanced RCC, from initial presentation through workup and to eventual diagnosis. The case features late-onset symptoms, extensive paraneoplastic phenomena, and significant physical examination findings. We also review the literature available on RCC and critically analyze inefficiencies of the workup retrospectively.

Keywords: RCC; advanced renal cell carcinoma; metastatic; paraneoplastic.

PubMed Disclaimer

Conflict of interest statement

Declaration of Conflicting Interests: The author(s) declared no potential conflicts of interest with respect to the research, authorship, and/or publication of this article.

Figures

Figure 1.
Figure 1.
Computed tomography scan of the renal malignancy.
See this image and copyright information in PMC

References

    1. Siegel RL, Miller KD, Jemal A. Cancer statistics, 2018. CA Cancer J Clin. 2018;68:7-30. - PubMed
    1. Garnick MB. Primary neoplasms of the kidney. In: Brady HR, Wilcox CS, eds. Therapy in Nephrology and Hypertension: A Companion to Brenner and Rector’s—The Kidney. Philadelphia, PA: WB Saunders; 1998:337-340.
    1. Siegel R, Ward E, Brawley O, Jemal A. Cancer statistics, 2011: the impact of eliminating socioeconomic and racial disparities on premature cancer deaths. CA Cancer J Clin. 2011;61:212-236. - PubMed
    1. Thompson RH, Ordonez MA, Iasonos A, et al. Renal cell carcinoma in young and old—is there a difference? J Urol. 2008;180:1262-1266. - PMC - PubMed
    1. Hu J, Mao Y, White K. Renal cell carcinoma and occupational exposure to chemicals in Canada. Occup Med (Lond). 2002;52:157-164. - PubMed

Publication types

LinkOut - more resources