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. 2018 Oct;24(10):1895-1901.
doi: 10.3201/eid2410.171194.

Multilocus Sequence Typing of Mycoplasma pneumoniae, Japan, 2002-2016

Mariko Ando, Miyuki Morozumi, Yoko Adachi, Kimiko Ubukata, Satoshi Iwata

Multilocus Sequence Typing of Mycoplasma pneumoniae, Japan, 2002-2016

Mariko Ando et al. Emerg Infect Dis. 2018 Oct.

Abstract

In Japan, Mycoplasma pneumoniae resistance to macrolides is high. To compare sequence types (STs) of susceptible and resistant isolates, we performed multilocus sequence typing for 417 isolates obtained in Japan during 2002-2016. The most prevalent ST overall was ST3, for macrolide-resistant was ST19, and for macrolide-susceptible were ST14 and ST7.

Keywords: Japan; MLST; Mycoplasma pneumoniae; bacteria; macrolide-resistant Mycoplasma pneumoniae; macrolide-sensitive Mycoplasma pneumoniae; multilocus sequence typing.

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Figures

Figure 1
Figure 1
Multilocus sequence typing results for 232 macrolide-susceptible and 185 macrolide-resistant Mycoplasma pneumoniae isolates, Japan, 2002–2016. Ten STs were identified for macrolide-susceptible and 12 STs for macrolide-resistant M. pneumoniae. ST, sequence type.
Figure 2
Figure 2
Relationship between CC and ST for Mycoplasma pneumoniae isolates by eBURST version 3.1 analysis (http://eburst.mlst.net/v3/mlst_datasets/). Data included 417 strains from Japan, 2002–2016, and 62 strains isolated from the United Kingdom, the United States, China, and France. For all isolates, 24 STs were identified. The size of each circle is proportional to the number of isolates for each ST. Red indicates isolates detected in Japan only; blue indicates isolates detected in the United Kingdom, the United States, China, and France but not Japan; black indicates isolates detected in all 5 countries. CC, clonal complex; ST, sequence type.
See this image and copyright information in PMC

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