doi: 10.1016/0006-291x(86)91073-9.
Identification of NGF receptor in chromatin of melanoma cells using monoclonal antibody to cell surface NGF receptor
- PMID: 3022715
- DOI: 10.1016/0006-291x(86)91073-9
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Identification of NGF receptor in chromatin of melanoma cells using monoclonal antibody to cell surface NGF receptor
Biochem Biophys Res Commun.
.
Abstract
A 230 KDa species of Nerve Growth Factor (NGF) receptor was immunoprecipitated from EcoRI-digested chromatin of melanoma cells using a monoclonal antibody to the 75 KDa cell surface NGF receptor. The chromatin NGF receptor was shown to exist tightly bound to DNase II-sensitive sequences which, upon growth factor binding, became resistant to DNase II digestion.
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