Sepsis: Therapeutic Potential of Immunosuppression versus Immunostimulation

Emanuele Rezoagli^{1

2}, Claire H Masterson¹, Sean D McCarthy¹, John G Laffey^{1

2}

Affiliations

¹ 1 Lung Biology Group, Regenerative Medicine Institute (REMEDI) at CÚRAM Centre for Research in Medical Devices, National University of Ireland Galway, Galway, Ireland; and.
² 2 Department of Anaesthesia and Intensive Care Medicine, Galway University Hospitals, Galway, Ireland.

Comment

Emanuele Rezoagli et al. Am J Respir Cell Mol Biol. 2019 Jan.

. 2019 Jan;60(1):128-130.

doi: 10.1165/rcmb.2018-0284RO.

Emanuele Rezoagli^{1

2}, Claire H Masterson¹, Sean D McCarthy¹, John G Laffey^{1

2}

¹ 1 Lung Biology Group, Regenerative Medicine Institute (REMEDI) at CÚRAM Centre for Research in Medical Devices, National University of Ireland Galway, Galway, Ireland; and.
² 2 Department of Anaesthesia and Intensive Care Medicine, Galway University Hospitals, Galway, Ireland.

No abstract available

Comment on

Arid5a exacerbates IFN-γ-mediated septic shock by stabilizing T-bet mRNA.
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Effect of Mesenchymal Stromal Cells on T Cells in a Septic Context: Immunosuppression or Immunostimulation?
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Interleukin-7 restores lymphocytes in septic shock: the IRIS-7 randomized clinical trial.
Francois B, Jeannet R, Daix T, Walton AH, Shotwell MS, Unsinger J, Monneret G, Rimmelé T, Blood T, Morre M, Gregoire A, Mayo GA, Blood J, Durum SK, Sherwood ER, Hotchkiss RS. Francois B, et al. JCI Insight. 2018 Mar 8;3(5):e98960. doi: 10.1172/jci.insight.98960. JCI Insight. 2018. PMID: 29515037 Free PMC article. Clinical Trial.