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Review
. 2019 Mar 20;36(3):490-530.
doi: 10.1039/c8np00032h.

Tryptophol and derivatives: natural occurrence and applications to the synthesis of bioactive compounds

Alessandro Palmieri  1 , Marino Petrini
Affiliations
Review

Tryptophol and derivatives: natural occurrence and applications to the synthesis of bioactive compounds

Alessandro Palmieri et al. Nat Prod Rep. .

Abstract

Covering: up to 2018 Tryptophol (indole-3-ethanol) is a metabolite produced by plants, bacteria, fungi and sponges. This review reports on the natural occurrence, bioactivity and various synthetic approaches to the preparation of tryptophol and its derivatives. Syntheses of various naturally occurring tryptophol derivatives known for their enhanced pharmacological profile are also presented.

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