Antigens expressed by human B lymphocytes and myeloid stem cells
- PMID: 302314
- PMCID: PMC2180819
- DOI: 10.1084/jem.146.4.1143
Antigens expressed by human B lymphocytes and myeloid stem cells
Abstract
Antisera prepared against papain-digested spleen cell membranes were known to by cytotoxic for normal and neoplastic human B lymphocytes and for a majority of acute and chronic myeloid leukemic cells. It is now shown that these antisera are also cytotoxic for normal myeloid stem cells (CFU-C), thus providing a probable explanation for their occurrence in myeloid neoplasia.
