Fungi Enter the Stage of Colon Carcinogenesis
- PMID: 30231977
- DOI: 10.1016/j.immuni.2018.09.002
Fungi Enter the Stage of Colon Carcinogenesis
Abstract
The significant contribution of intestinal bacteria for the pathogenesis of colorectal cancer is widely accepted by now. In this issue of Immunity, two articles by Malik et al. (2018) and Wang et al. (2018) highlight the role of commensal fungi, which so far have been underestimated.
Copyright © 2018 Elsevier Inc. All rights reserved.
Comment on
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The Adaptor Protein CARD9 Protects against Colon Cancer by Restricting Mycobiota-Mediated Expansion of Myeloid-Derived Suppressor Cells.Immunity. 2018 Sep 18;49(3):504-514.e4. doi: 10.1016/j.immuni.2018.08.018. Immunity. 2018. PMID: 30231984 Free PMC article.
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SYK-CARD9 Signaling Axis Promotes Gut Fungi-Mediated Inflammasome Activation to Restrict Colitis and Colon Cancer.Immunity. 2018 Sep 18;49(3):515-530.e5. doi: 10.1016/j.immuni.2018.08.024. Immunity. 2018. PMID: 30231985 Free PMC article.
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