Commentary: Immune System Dysregulation During Spaceflight: Potential Countermeasures for Deep Space Exploration Missions

Joseph J Bevelacqua¹, S M J Mortazavi^{2

3}

Affiliations

¹ Bevelacqua Resources, Richland, WA, United States.
² Diagnostic Imaging Department, Fox Chase Cancer Center, Philadelphia, PA, United States.
³ INIRPRC, Shiraz University of Medical Sciences, Shiraz, Iran.

Comment

Joseph J Bevelacqua et al. Front Immunol. 2018.

. 2018 Sep 4:9:2024.

doi: 10.3389/fimmu.2018.02024. eCollection 2018.

Joseph J Bevelacqua¹, S M J Mortazavi^{2

3}

¹ Bevelacqua Resources, Richland, WA, United States.
² Diagnostic Imaging Department, Fox Chase Cancer Center, Philadelphia, PA, United States.
³ INIRPRC, Shiraz University of Medical Sciences, Shiraz, Iran.

No abstract available

Keywords: countermeasures; deep space missions; immune system; radioadaptation; space radiation.

Comment on

Immune System Dysregulation During Spaceflight: Potential Countermeasures for Deep Space Exploration Missions.
Crucian BE, Choukèr A, Simpson RJ, Mehta S, Marshall G, Smith SM, Zwart SR, Heer M, Ponomarev S, Whitmire A, Frippiat JP, Douglas GL, Lorenzi H, Buchheim JI, Makedonas G, Ginsburg GS, Ott CM, Pierson DL, Krieger SS, Baecker N, Sams C. Crucian BE, et al. Front Immunol. 2018 Jun 28;9:1437. doi: 10.3389/fimmu.2018.01437. eCollection 2018. Front Immunol. 2018. PMID: 30018614 Free PMC article. Review.

Poor Understanding of Radiation Profiles in Deep Space Causes Inaccurate Findings and Misleading Conclusions.
J J B, S M J M. J J B, et al. J Biomed Phys Eng. 2019 Oct 1;9(5):587-588. doi: 10.31661/jbpe.v0i0.1021. eCollection 2019 Oct. J Biomed Phys Eng. 2019. PMID: 31750273 Free PMC article.

1. Crucian BE, Choukèr A, Simpson RJ, Mehta S, Marshall G, Smith SM, et al. . Immune system dysregulation during spaceflight: potential countermeasures for deep space exploration missions. Front. Immunol. (2018). 9:1437. 10.3389/fimmu.2018.01437 - DOI - PMC - PubMed
1. Scott BR. Radiation-hormesis phenotypes, the related mechanisms and implications for disease prevention and therapy. J Cell Commun Signal. (2014) 8:341–52. 10.1007/s12079-014-0250-x - DOI - PMC - PubMed
1. Stowe RP, Sams CF, Mehta SK, Kaur I, Jones ML, Feeback DL, et al. . Leukocyte subsets and neutrophil function after short-term spaceflight. J Leukoc Biol. (1999) 65:179–86. - PubMed
1. Stowe RP, Sams CF, Pierson DL. Adrenocortical and immune responses following short- and long-duration spaceflight. Aviat Space Environ Med. (2011) 82:627–34. 10.3357/ASEM.2980.2011 - DOI - PubMed
1. Austin AW, Patterson SM, Ziegler MG, Mills PJ. Plasma volume and flight duration effects on post-spaceflight soluble adhesion molecules. Aviat Space Environ Med. (2014) 85:912–8. 10.3357/ASEM.3959.2014 - DOI - PubMed