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. 2018 Oct;16(4):3574-3578.
doi: 10.3892/etm.2018.6640. Epub 2018 Aug 22.

Effects of atrial fibrillation on complications and prognosis of patients receiving emergency PCI after acute myocardial infarction

Yingchun Zhang  1 , Lingzhi Zhang  2 , Hongzhi Zheng  3 , Hongfen Chen  1
Affiliations

Effects of atrial fibrillation on complications and prognosis of patients receiving emergency PCI after acute myocardial infarction

Yingchun Zhang et al. Exp Ther Med. 2018 Oct.

Abstract

The effects of atrial fibrillation on complications and prognosis of patients receiving emergency percutaneous coronary intervention after acute myocardial infarction (AMI) were investigated. Eighty AMI patients treated with interventional vascular recanalization in the Affiliated Hospital of Weifang Medical University (Weifang, China) from July 2015 to October 2016 were selected, including 40 patients complicated with atrial fibrillation before operation (control group) and 40 patients without atrial fibrillation before operation (observation group). The systolic blood pressure, diastolic blood pressure, heart rate, arrhythmia and common complications after MI were compared. Changes in the coronary artery thrombolysis in myocardial infarction (TIMI) flow grade and left ventricular ejection fraction (LVEF) of patients were also recorded. Moreover, changes in brain natriuretic peptide (BNP) levels were compared. The recovery time of myocardial enzyme and total troponin in both groups was recorded. The systolic and diastolic blood pressure in the observation group were significantly higher than those in the control group (p<0.05). During the intervention, the total proportion of patients with ventricular arrhythmia, atrial arrhythmia, atrioventricular block and sinus tachycardia in the observation group was significantly lower than that in the control group (p<0.05). The total proportion of common complications after MI in the observation group was obviously lower than that in the control group (p<0.05). Coronary artery TIMI flow grades and LVEFs in the observation group were obviously higher than those in the control group. BNP levels in the observation group were significantly lower than those in the control group. The recovery time of myocardial enzyme and total troponin in the observation group was significantly earlier than that in the control group. Atrial fibrillation has a certain negative effect on the circulatory function in patients with AMI after the interventional therapy, and the proportions of arrhythmia and complications in patients after MI are increased at the same time, so the postoperative recovery of patients is slow with many complications.

Keywords: acute myocardial infarction; atrial fibrillation; complications; percutaneous coronary intervention.

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Figures

Figure 1.
Figure 1.
Changes in coronary artery TIMI blood flow grades of patients at different time-points before and after operation. Coronary artery TIMI flow grades in the observation group immediately after operation, and at 3 months and 1 year after operation are obviously higher than those in the control group during the same period (p<0.05). TIMI, thrombolysis in myocardial infarction.
Figure 2.
Figure 2.
Changes in LVEFs of patients at different time-points before and after operation. LVEFs in the observation group immediately after operation, and at 3 months and 1 year after operation are obviously higher than those in the control group during the same period (p<0.05). LVEF, left ventricular ejection fraction.
Figure 3.
Figure 3.
Changes in the BNP levels of patients at different time-points before and after operation. At 1 week and 1 month after operation, the BNP levels in the observation group are significantly lower than those in the control group during the same period (p<0.05). BNP, brain natriuretic peptide.
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